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#1 Heidi

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Posted 19 November 2009 - 07:52 PM

Cornell University has developed a direct DNA test for LFS that will be commercially available in the near future.

BINT SAFIERA 2000 Bay mare
SHAMS EL BINA 2002 Bay mare
NAKHDA AL SHAIB 2004 Grey Gelding<---- AL
SIHR JAWHER 2006 Bay Stallion
NADEERAH ALIAH 2006 Bay mare
ZAHRAN HAMRAH 2006 Grey mare
SHAMS FIDAT 2012 grey filly SKYLER the 1/2 Arabian pinto wonder horse


#2 Suellen Taylor

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Posted 19 November 2009 - 07:58 PM

That is such good news...now for JE and GPT..hopefully in the near future.

I think there are probably more JE foals than the others, but any test is a good test!

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#3 Juniper

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Posted 19 November 2009 - 09:57 PM

so sooo happy!
The progress is so fast, pretty soon we won't be blind anymore.

#4 chiron

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Posted 19 November 2009 - 10:53 PM

:WELCOME56: :1233_hand_clapping:

Is there any chance that those of us who were first in line to supply samples might get a little discount??? That sounds so petty I know, but I'm soooooo broke right now but really really anxious for results on a couple of the horses here..

Big Kudos to Cornell & all who helped support they're research. Job well done.

Next step JES & GPT :WELCOME56:
Non Illigiitamus Carborundum

#5 dakhilah

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Posted 21 November 2009 - 08:03 PM

Hi All,

That is really GREAT!!!!!!!


Greetings sas.

#6 Trish aka JMO

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Posted 23 November 2009 - 12:58 AM

That is just the most wonderful news and all those who provided samples I :1233_hand_clapping: you for making this happen.

I'm amazed with the small steps that we started with & just how far we come..... :)

So of 5 genetic problems we know about we have 3 tests available and 2 to go.... :th_cool:

#7 Melissa

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Posted 23 November 2009 - 01:01 AM

This is so great to read!!!

Melissa & Matt Raulerson
Jete' Arabians Home to:
Raja El Halimaar (El Halimaar x Mageenaa) 2001 Stallion
SCID Clear, LFS Clear, CA N/N

Hali Inasa (Abraxas Halimaar x Georgia Inasa) 2002 Mare
Zandai Ibn Zeidan (Zandai Abu Zeidan x MFA Tassideh) 2002 Gelding
Zandai Zavoniyah (Zandai Ibn Omar x Zandai Saouda) 2004 Mare CA N/N
Zandai Om Noor (Zandai Ibn Omar x Zandai Saouda) 2005 Mare CA N/N

Yara MM (Raja El Halimaar x Zandai Zavoniyah) 2012 Filly CA N/N (By Parentage)


#8 Juniper

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Posted 24 November 2009 - 09:19 PM

Can somebody post the link to the official release in this section?
I would like to share with others but don't want to go through 100ds of posts.
I know I have seen one somewhere but where?

#9 Juniper

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Posted 24 November 2009 - 09:24 PM

just read this that a friend found.
LFS test - S Africa

Lavender Foal Syndrome Test in Arabian horses is now available!

The Onderstepoort Veterinary Genetics Laboratory has recently found the mutation responsible for the genetic condition known as Lavender Foal Syndrome (LFS) in Arabian horses and has developed a DNA based test for this condition. The mode of inheritance of LFS and SCID (Severe Combined Immunodeficiency Disease) is similar, both are autosomal recessive and test results indicate whether an animal has 2 defective alleles (affected), one defective allele (carrier) or 2 normal alleles (clear). The affected animal has a pale blue / lavender coat colour and severe neurological deficits that are incompatible with life and will result in death within hours to a maximum of a few days. The clear and carrier animals are completely normal. Similar to SCID, an affected animal can only be produced when 2 carriers are bred to each other, but no affected animals will be produced when a clear and carrier are bred to each other. A test and selective breeding strategy is, therefore, again recommended for LFS, similar to that done with SCID that resulted in a decrease of SCID carrier prevalence in the South African Arabian horse population from 8.3% to 5.2% since 2004.

The discovery of the LFS mutation and development of the genetic test is a significant scientific finding and will make a valuable contribution to the knowledge of the genetics of the horse. The discovery has also highlighted the value of the close cooperation between our laboratory at the Faculty of Veterinary Science and the Arabian horse breeding community. Without the support and samples supplied by breeders locally this achievement would not be possible. Not only is our Arabian breeding community unique in its support of scientific study, particularly in terms of genetics but also in the application of genetic disease test results. The open test and selective breeding strategy used to reduce the prevalence of SCID is also an indication of the local Arabian breeder’s commitment to removing unwanted traits from our stock while maintaining the favourable genetics.


Two independent tests?

#10 phanilah

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Posted 24 November 2009 - 09:45 PM

The official release re: the Cornell test will come when the embargo is released on the scientific manuscript pending publication and the licensing details are finalized with the lab(s) who will commerically offer the test; as Cornell is not set up to commerically run the test.

The South African test is a separate test, offered by a lab in South Africa based on work they have done. I haven't seen any published work regarding this test and am not sure if they have anything submitted for publication or not.

Beth
si hoc legere scis, nimium eruditionis habes

#11 Meralee

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Posted 02 June 2010 - 02:33 PM

I sent in samples for the reserch and I am happy to report that BOTH Golden Desra and Jubilee Princess are NON CARRIERS!!!
I downloaded the info to get Jub tested for CA,I hope to breed her next year. Her Dad is SCIDS free so unless I fall in love with a carrier will not be testing her for that. Mer Here is the "princess" :)

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#12 JRS Gentle Hills

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Posted 16 June 2010 - 04:22 PM

Do they have a company in the US doing this test?

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PS Nominated
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Strain: Bint El Behreyn

Arlene Magid write-ups available on each



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#13 Juniper

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Posted 16 June 2010 - 05:04 PM

Do they have a company in the US doing this test?



It should be available very soon (a month?) from Cornell if I understood well!

#14 JRS Gentle Hills

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Posted 16 June 2010 - 05:21 PM

It should be available very soon (a month?) from Cornell if I understood well!


Oh, ok. Thanks!

JRs Gentle Hills Farm
www.jrsgentlehills.com

STRAIGHT EGYPTIANS - DISPERSAL SALE.

JRs Al Shabah al Aswad "The Black Phantom", Homozygous Black,
PS Nominated
TDR White Stone (exported) x Alia Kateefa (by exported Ibn Layalia)
Pure in the Strain, Saqlawi

JRs Nabiel Shaikh, Flaxen Chestnut, no Minstril
Shaikh Al Glory x Schzerade Petite.
Strain: Bint El Behreyn

Arlene Magid write-ups available on each



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#15 Seglavi

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Posted 22 July 2010 - 01:20 PM

Where the heck is the test?
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#16 DJ Sheldon

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Posted 22 July 2010 - 01:22 PM

Good question. It was my understanding it was going to "go to market" last week. Still waiting......

#17 firepanther

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Posted 27 July 2010 - 11:08 AM

I had never heard of this until I read up on it at the Institute for the Desert Arabian Horse! I'm so glad I'm doing lots of research
From reading the article it sounds like it should be available soon
"Cornell University, where the research was conducted, is expected to announce in the next few weeks whether they will offer the test or if it will be licensed to a commercial lab."
Not sure exactly when that phrase was published, but hopefully it will be available shortly!

#18 phanilah

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Posted 27 July 2010 - 05:56 PM

They are going through the final administrative hoops, so everyday I check my email for the update. :2_horses:

Beth
si hoc legere scis, nimium eruditionis habes

#19 diane

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Posted 28 July 2010 - 08:53 AM

They are going through the final administrative hoops, so everyday I check my email for the update. :monopoly_horse:

Beth

Thanks, Beth. Looking forward to good news :68416045.wGDPMlLK.popcorn:
cheers, diane
Agecroft, Australia


Is there an elephant in the room?

#20 V6297

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Posted 13 August 2010 - 12:50 PM

It's up:

http://ahdc.vet.corn...p?testcode=LFSG




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